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A stratified model for health outcomes in ankylosing spondylitis
Machado, P; Landewé, R; Braun, J; Hermann, KG; Baraliakos, X; Baker, D; Hsu, B; van der Heijde, DOBJECTIVE: To investigate the relationships between several health outcomes in ankylosing spondylitis (AS). METHODS: Baseline pretreatment data from 214 patients with AS participating in the AS Study for the Evaluation of Recombinant Infliximab Therapy were analysed. Measures of health-related quality of life (HRQoL) and physical function were used as dependent variables in linear regression analysis. Associat...
Both structural damage and inflammation of the spine contribute to impairment o...
Machado, P; Landewé, R; Braun, J; Hermann, KG; Baker, D; van der Heijde, DOBJECTIVE: To study the relationship between spinal mobility, radiographic damage of the spine and spinal inflammation as assessed by MRI in patients with ankylosing spondylitis (AS). METHODS: In this subanalysis of the Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy cohort, 214 patients, representing an 80% random sample, were investigated. Only baseline data were used. MRI i...
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