Biotransformation enzymes catalyze oxidation of a diversity of xenobiotics, doing a key role in its detoxication. CYP1A and GST expression, induced by pollutants, seems to be highly conserved across vertebrate taxa. Since this system acts as a defense mechanism, the intra or interspecies differences have been attributed to adaptations to different habitats and trophic strategies. Thus, the main goal of this stu...
O principal objectivo deste trabalho foi avaliar como a conjugação de xenobióticos com o glutationo mediada por glutationo S-transferase (E C 2.5.1.18, cGST) citoplasmáticos é afectada pelo ambiente da bacia, em particular pela concentração salina do meio.
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