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Myocardial perfusion grade after late infarct artery recanalization is associat...
Steigen, T; Christopher, E; Buller, C; Mancini, G; Jorapur, V; Cantor, W; Rankin, J; Thomas, B; Webb, J; Kronsberg, S; Atchison, D; Lamas, G; Hochman, JBACKGROUND: Whether myocardial perfusion grade (MPG) following late recanalization of infarct-related arteries (IRAs) predicts left ventricular (LV) function recovery beyond the acute phase of myocardial infarction (MI) is unknown. METHODS AND RESULTS: The Total Occlusion Study of Canada-2 enrolled stable patients with a persistently occluded IRA beyond 24 hours and up to 28 days post-MI. We studied the relati...
Impact of stress testing before percutaneous coronary intervention or medical m...
Cantor, W; Baptista, S; Srinivas, V; Pearte, C; Menon, V; Sadowski, Z; Ross, J; Meciar, P; Nikolsky, E; Forman, S; Lamas, G; Hochman, JBackground—In the Occluded Artery Trial (OAT), 2201 stable patients with an occluded infarctrelated artery (IRA) were randomized to percutaneous coronary intervention (PCI) or optimal medical treatment alone (MED). There was no difference in the primary endpoint of death, re-MI or heart failure (CHF). We examined the prognostic impact of pre-randomization stress testing. Methods—Stress testing was required by p...
Percutaneous coronary intervention in the occluded artery trial: procedural suc...
Buller, C; Rankin, J; Carere, R; Buszman, P; Pfisterer, M; Dzavik, V; Thomas, B; Forman, S; Ruzyllo, W; Mancini, G; Michalis, L; Abreu, G; Lamas, GBACKGROUND: The Occluded Artery Trial (OAT) was a 2,201-patient randomized clinical trial comparing routine stent-based percutaneous coronary intervention (PCI) versus optimal medical therapy alone in stable myocardial infarction (MI) survivors with persistent infarct-related artery occlusion identified day 3 to 28 post MI. Intent-to-treat analysis showed no difference between strategies with respect to the inc...
Randomized trial of percutaneous coronary intervention for subacute infarct-rel...
Dzavík, V; Buller, C; Lamas, G; Rankin, J; Mancini, G; Cantor, W; Carere, R; Ross, J; Atchison, D; Forman, S; Thomas, B; Buszman, P; Vozzi, C; Glanz, ABACKGROUND: In the present study, we sought to determine whether opening a persistently occluded infarct-related artery (IRA) by percutaneous coronary intervention (PCI) in patients beyond the acute phase of myocardial infarction (MI) improves patency and indices of left ventricular (LV) size and function. METHODS AND RESULTS: Between May 2000 and July 2005, 381 patients with an occluded native IRA 3 to 28 day...
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