Encontrados 3 documentos, a visualizar página 1 de 1
Sources of hepatic triglyceride accumulation during high-fat feeding in the hea...
Delgado, T. C.; Pinheiro, D.; Caldeira, M.; Castro, M. M. C. A.; Geraldes, C. F. G. C.; López-Larrubia, P.; Cerdán, S.; Jones, J. G.Hepatic triglyceride (HTG) accumulation from peripheral dietary sources and from endogenous de novo lipogenesis (DNL) was quantified in adult Sprague-Dawley rats by combining in vivo localized 1H MRS measurement of total hepatic lipid with a novel ex vivo 2H NMR analysis of HTG 2H enrichment from 2H-enriched body water. The methodology for DNL determination needs further validation against standard methodologie...
Targeting of lanthanide(III) chelates of DOTA-type glycoconjugates to the hepat...
Prata, M. I. M.; Santos, A. C.; Torres, S.; André, J. P.; Martins, J. A.; Neves, M.; García-Martín, M. L.; Rodrigues, T. B.; López-Larrubia, P.The characterization of a new class of hydrophilic liver-targeted agents for gamma-scintigraphy and MRI, consisting, respectively, of [153Sm]3+ or Gd3+ complexes of DOTA monoamide or bisamide linked glycoconjugates (DOTA = 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), is reported. In vitro studies show high uptake of radiolabeled [153Sm]-DOTAGal2 by the human hepatocyte carcinoma cell line Hep G2 c...
Targeting of lanthanide(III) chelates of DOTA-type glycoconjugates to the hepat...
Prata, M. I. M.; Santos, A. C.; Torres, Susana; André, João P.; Martins, J. A. R.; Neves, M.; García Martín, M. L.; Rodrigues, T. B.; López Larrubia, P.The characterization of a new class of hydrophilic liver-targeted agents for gamma-scintigraphy and MRI, consisting, respectively, of [153Sm]3+ or Gd3+ complexes of DOTA monoamide or bisamide linked glycoconjugates (DOTA = 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), is reported. In vitro studies show high uptake of radiolabeled 153SmDOTAGal2 by the human hepatocyte carcinoma cell line Hep G2 cont...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||