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Relationship of PON1 192 and 55 gene polymorphisms to calcific valvular aortic ...
Moura, Luís M.; Faria, Susana; Brito, Miguel; Pinto, Fausto J.; Kristensen, Steen D.; Barros, Isabel M.; Rajamannan, Nalini; Rocha-Gonçalves, FranciscoIntroduction and Objectives - Paraoxonases may exert anti-atherogenic action by reducing lipid peroxidation. Previous studies examined associations between polymorphisms in the paraoxonase 1 (PON1) gene and development of coronary artery disease (CAD), with inconsistent results. Given the similarities in clinical and pathophysiological risk factors of CAD and calcific aortic valve stenosis (CAVS), we postulated...
Data: 2012
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Origem: Repositório Científico do Instituto Politécnico de Lisboa
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