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Starch-poly(epsilon-caprolactone) and starch-poly(lactic acid) fibre-mesh scaff...
Gomes, Manuela E.; Azevedo, Helena S.; Moreira, A. R.; Ellã, V.; Kellomaki, M.; Reis, R. L.In scaffold-based tissue engineering strategies, the successful regeneration of tissues from matrixproducing connective tissue cells or anchorage-dependent cells (e.g. osteoblasts) relies on the use of a suitable scaffold. This study describes the development and characterization of SPCL (starch with !-polycaprolactone, 30 : 70%) and SPLA [starch with poly(lactic acid), 30 : 70%] fibre-meshes, aimed at applicat...
Development of a bioactive glass fiber reinforced starch-polycaprolactone compo...
Jukola, H.; Nikkola, L.; Gomes, Manuela E.; Chiellini, F.; Tukiainen, M.; Kellomaki, M.; Chiellini, E.; Reis, R. L.; Ashammakhi, N.For bone regeneration and repair, combinations of different materials are often needed. Biodegradable polymers are often combined with osteoconductive materials, such as bioactive glass (BaG), which can also improve the mechanical properties of the composite. The aim of this work was to develop and characterize BaG fiber reinforced starch–poly-ecaprolactone (SPCL) composite. Sheets of SPCL (30/70 wt %) were pro...
Studies of P(L/D)LA 96/4 non-woven scaffolds and fibres; properties, wettabilit...
Ellã, V.; Gomes, Manuela E.; Reis, R. L.; Tormala, P.; Kellomaki, M.Poly(L/D)lactide 96/4 fibres with diameters of 50 and 80 microm were produced. The smaller diameter fibres were carded and needle punched to form a non-woven mat. Fibres and non-woven mats were hydrolysed for a period of 20 weeks. Fibres and pressed non-woven discs were treated with low-temperature oxygen plasma and alkaline KOH hydrolysis and ethanol washing was used as a reference treatment. The non-wovens lo...
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