Encontrados 8 documentos, a visualizar página 1 de 1
The effects of cover crops and conventional tillage on soil and runoff loss in ...
Gómez, J.A.; Llewellyn, C.; Basch, G.; Sutton, P.B.; Dyson, J.S.; Jones, C.A.Cover crops (CC) in vineyards and olive groves provide an alternative to conventional tillage (CT) for land management. Runoff, sediment and nutrient loss from six sites in France, Spain and Portugal were compared over 3–4 yr. In general, runoff loss was not significantly reduced by the CC alternatives: average annual runoff coefficients ranged from 4.9 to 22.8% in CT compared with 1.9– 25% in the CC alternatives...
Molecular and phenotypic characterisation of paediatric glioma cell lines as mo...
Bax, Dorine A.; Little, Suzie; Gaspar, Nathalie; Perryman, Lara; Marshall, Lynley; Viana, Marta Pereira; Jones, Tania A.; Williams, Richard D.Background: Although paediatric high grade gliomas resemble their adult counterparts in many ways, there appear to be distinct clinical and biological differences. One important factor hampering the development of new targeted therapies is the relative lack of cell lines derived from childhood glioma patients, as it is unclear whether the well-established adult lines commonly used are representative of the unde...
Analysis of EGFR Overexpression, EGFR gene amplification and the EGFRvIII Mutat...
Viana, Marta Pereira; Lopes, José M.; Little, Suzie; Milanezi, Fernanda; Basto, Diana; Pardal, Fernando; Jones, C.; Reis, R. M.Background: Patients with malignant gliomas do not respond to any current therapy. Epidermal growth factor receptor (EGFR) controls several oncogenic processes, being frequently up-regulated in gliomas due to overexpression, gene amplification and gene mutation. EGFR inhibitors are being tried in gliomas, yet the molecular determinants of therapeutic response are unclear. Materials and Methods: EGFR overexpress...
Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutat...
Viana-Pereira, M; Lopes, JM; Little, S; Milanezi, F; Basto, D; Pardal, F; Jones, C; Reis, RMBACKGROUND: Patients with malignant gliomas do not respond to any current therapy. Epidermal growth factor receptor (EGFR) controls several oncogenic processes, being frequently up-regulated in gliomas due to overexpression, gene amplification and gene mutation. EGFR inhibitors are being tried in gliomas, yet the molecular determinants of therapeutic response are unclear. MATERIALS AND METHODS: EGFR overexpress...
Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutat...
Viana-Pereira, M; Lopes, JM; Little, S; Milanezi, F; Basto, D; Pardal, F; Jones, C; Reis, RMBACKGROUND: Patients with malignant gliomas do not respond to any current therapy. Epidermal growth factor receptor (EGFR) controls several oncogenic processes, being frequently up-regulated in gliomas due to overexpression, gene amplification and gene mutation. EGFR inhibitors are being tried in gliomas, yet the molecular determinants of therapeutic response are unclear. MATERIALS AND METHODS: EGFR overexpress...
Understanding posttraumatic stress disorder-related symptoms after critical car...
Granja C; Gomes E; Amaro A; Orquídea Ribeiro; Jones C; Carneiro; Costa Pereira A; JMIP Study GroupObjective: To assess the factual and delusional memories reported by intensive care unit survivors and its relationship with the development of Posttraumatic Stress Syndrome (PTSS). Design: Multicenter observational cohort study. Setting: Nine Portuguese intensive care units, as part of a multicenter study. Methods and Patients: Between January and June 2005, 1,174 patients were admitted across the nine inte...
EGFR amplification and lack of activating mutations in metaplastic breast carci...
Reis Filho, Jorge S.; Pinheiro, Céline; Lambros, M. B. K.; Milanezi, Fernanda; Carvalho, Silvia; Savage, K.; Simpson, Pete T.; Jones, C.; Swift, S.Metaplastic breast carcinomas are reported to harbour epidermal growth factor receptor (EGFR) overexpression in up to 80% of the cases, but EGFR gene amplification is the underlying genetic mechanism in around one-third of these. In this study, EGFR gene amplification as defined by chromogenic in situ hybridization and protein overexpression was examined in a cohort of 47 metaplastic breast carcinomas. Furtherm...
Microperfusion studies on the permeability of retinal vessels. A new model demo...
Murta, J. N.; Cunha-Vaz, J. G.; Sabo, C. A.; Jones, C. W.; Laski, M. E.We developed an experimental model to study the permeability of individual retinal vessels in vitro using microperfusion techniques adapted from kidney tubule studies. The retinal vessels were isolated by freehand dissection and mounted on a microperfusion apparatus. When inulin was perfused luminally, it was diluted to 80.2 +/- 2.3% of its initial concentration. However, no radioactive leak into the bath side ...
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