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Newborn screening for biotinidase deficiency in Brazil : biochemical and molecu...
Camargo Neto, Eurico; Schulte, Jaqueline; Rubim, Rosália; Lewis, E.; De Mari, Jurema de Fatima; Castilhos, C.; Brites, Adriana; Giugliani, RobertoBiotinidase deficiency is an inherited metabolic disorder characterized by neurological and cutaneous symptoms. Fortunately, it can be treated and the symptoms prevented by oral administration of the vitamin biotin. Using dried blood-soaked filter paper cards, biotinidase activity was determined in the sera of 225,136 newborns in Brazil. Mutation analysis performed on DNA from 21 babies with low serum biotinida...
Effects of restoration management on the estuarine isopod Cyathura carinata: me...
Ferreira, S.; Brandão, A.; Baeta, A.; Neto, J.; Lillebø, A.; Jensen, K.; Pardal, M.Abstract A restoration programme was introduced in the Mondego Estuary (Portugal) to recover seagrass beds of Zostera noltii endangered by eutrophication. A long-term survey of 10 years was used to assess the development of the processes involved, focusing one of the key species (Cyathura carinata, Isopoda). The mitigation measures implemented since 1998 (nutrient loading reduction, freshwater circulation impr...
Impact of microphallid trematodes on the survivorship, growth, and reproduction...
Ferreira, S. M.; Jensen, K. T.; Martins, P. A.; Sousa, S. F.; Marques, J. C.; Pardal, M. A.Crustaceans are second intermediate hosts to several microphallid species (Trematoda). Some of these parasites are potentially pathogenic or manipulative. A laboratory experiment was performed to assess the impact of microphallids on the survival, growth and fecundity of Cyathura carinata, a protogynous hermaphroditic isopod, widespread within European estuaries. For nearly 12 weeks, experimental populations of...
Infection characteristics of a trematode in an estuarine isopod: influence of s...
Ferreira, Susana M.; Jensen, K. Thomas.; Pardal, Miguel A.The estuarine isopod Cyathura carinata is a second intermediate host to microphallid trematodes, which use mud snails Hydrobia spp. and shorebirds as respectively first intermediate and final hosts. To identify processes responsible for infection patterns observed in C. carinata, a short-term microcosm experiment was conducted with both macroinvertebrates and one of their common parasites – Maritrema subdolum. ...
Trematodes in a Cyathura carinata population from a temperate intertidal estuar...
Jensen, K. Thomas; Ferreira, Susana M.; Pardal, Miguel A.A study was initiated to identify trematode patterns in Cyathura from two key sites in the Mondego Estuary: a Zostera-bed and a sand flat. The two subpopulations of Cyathura differ, as the annual recruitment success is much higher and more regular on the sandflat than on the Zostera-bed. Counting and sizing of trematode cysts inside the body of preserved Cyathura specimens enabled a description of trematode p...
Newborn screening for biotinidase deficiency in Brazil: biochemical and molecul...
C. Neto,E.; Schulte,J.; Rubim,R.; Lewis,E.; DeMari,J.; Castilhos,C.; Brites,A.; Giugliani,R.; Jensen,K.P.; Wolf,B.Biotinidase deficiency is an inherited metabolic disorder characterized by neurological and cutaneous symptoms. Fortunately, it can be treated and the symptoms prevented by oral administration of the vitamin biotin. Using dried blood-soaked filter paper cards, biotinidase activity was determined in the sera of 225,136 newborns in Brazil. Mutation analysis performed on DNA from 21 babies with low serum biotinida...
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