Encontrados 4 documentos, a visualizar página 1 de 1
A novel VIVO–pyrimidinone complex: synthesis, solution speciation and human ser...
Gonçalves, Gisela; Tomaz, Isabel; Correia, Isabel; Vieiros, Luís F.; Castro, M. M. C. A.; Avecilla, Fernando; Palacio, Lorena; Maestro, MiguelThe pyrimidinones mhcpe, 2-methyl-3H-5-hydroxy-6-carboxy-4-pyrimidinone ethyl ester (mhcpe, 1), 2,3- dimethyl-5-benzyloxy-6-carboxy-4-pyrimidinone ethyl ester (dbcpe, 2) and N-methyl-2,3-dimethyl-5- hydroxy-6-carboxyamido-4-pyrimidinone (N-MeHOPY, 3), are synthesized and their structures determined by single crystal X-ray diffraction. The acid–base properties of 1 are studied by potentiometric and spectrophotom...
Binding of oxovanadium(IV) complexes to blood serum albumins
Cobbina, Enoch; Mehtab, Sameena; Correia, Isabel; Gonçalves, Gisela; Tomaz, Isabel; Cavaco, Isabel Maria Palma Antunes; Jakusch, Tamás; Eneyedi, EvaIn this work the binding of VIVO2+ and VIVO-complexes to serum albumins {human serum albumin (HSA), bovine serum albumin (BSA) and porcine serum albumin (PSA)} are studied using circular dichroism (CD), electron paramagnetic resonance (EPR) and visible absorption spectroscopy. The results confirm previous findings that VIVO2+ occupies at least two types of binding sites on albumin: ‘the strong vanadium binding ...
Vanadium (IV and V) Complexes of Reduced Schiff Bases Derived from the Reaction...
Pessoa, João Costa; Marcão, Susana; Correia, Isabel; Gonçalves, Gisela; Dörnyei, Agnes; Kiss, Tamás; Jakusch, Tamás; Tomaz, IsabelThe reduced Schiff bases of salicylaldehyde [and o-vanillin (o-van)] with D,L- and L-diaminopropionic acid (DPA), designated by salDPA, and L-2,4-diaminopentanoic acid [ornithine (Orn)], designated by salOrn, as well as the VIVO2+ and VVO2+ complexes of salDPA were prepared. The compounds were characterised in the solid state and in solution. The structure of H4salDPA+Cl- was determined by X-ray diffraction. Co...
N,N'-Ethylenebis(pyridoxylideneiminato) and N,N'-Ethylenebis(pyridoxylaminato):...
Correia, Isabel; Pessoa, João Costa; Duarte, M. Teresa; Henriques, Rui T.; Piedade, M. Fátima M.; Veiros, Luís F.; Jakusch, Tamás; Kiss, TamásThe Schiff base N,Nprime-ethylenebis(pyridoxylideneiminato) (H2pyr2en, 1) was synthesized by reaction of pyridoxal with ethylenediamine; reduction of H2pyr2en with NaBH4 yielded the reduced Schiff base N,Nprime-ethylenebis(pyridoxylaminato) (H2Rpyr2en, 2); their crystal structures were determined by X-ray diffraction. The totally protonated forms of 1 and 2 correspond to H6L4+, and all protonation constants wer...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||