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Localization and Spreading of Diseases in Complex Networks

Staphylococcus epidermidis adhesion to modified polycarbonate surfaces : gold a...

Bacterial adhesion to a biomaterial surface is thought to be the key step in the infection of indwelling medical devices and constitutes an object of study in the demand to reduce nosocomial infections. In this work, specific modifications on polycarbonate outer layer were utilized as model surfaces for the study of the adhesion of Staphylococcus epidermidis, one of the main microorganisms responsible for nosoc...

Characterization of monoolein-based lipoplexes using fluorescence spectroscopy

Lipoplexes are commonly used as delivery systems in vitro and in vivo, the role of a neutral lipid as helper being of extreme importance in these systems. Cationic liposomes composed of dioctadecyldimethylammonium bromide (DODAB) with monoolein (MO) as a helper, at different molar ratios (1:2; 1:1 and 1:0.5) were prepared, and subsequently titrated to DNA. The structural and physicochemical properties of the li...

Domain formation in DODAB–cholesterol mixed systems monitored via nile red anis...

The effect of the cholesterol (Ch) on liposomes composed of the cationic lipid dioctadecyldimethylammonium bromide (DODAB) was assessed by studying both the steady-state and time-resolved fluorescence anisotropy of the dye Nile Red. The information obtained combined with analysis of the steady-state emission and luorescence lifetime of Nile Red (NR) for different cholesterol concentrations (5–50%) elucidated t...