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In-vitro bioactivity of starch thermoplastic/hydroxylapatite composite biomater...
Leonor, I. B.; Ito, A.; Onuma, K.; Kanzaki, N.; Reis, R. L.The in vitro bioactivity of a composite composed by a biodegradable starch-based polymeric matrix and hydroxyapatite fillers was investigated, in situ, as a function of immersion time in a simulated body fluid (SBF) using atomic force microscopy (AFM). The surface roughness of the composite started to increase after the initial 8 h because of both the degradation of the polymer matrix andthe nucleation of calci...
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vit...
Leonor, I. B.; Ito, A.; Onuma, K.; Kanzaki, N.; Zhong, Z. P.; Greenspan, D.; Reis, R. L.The present work investigates, in situ, the in vitro bioactivity of partially crystallized 45S5 Bioglass! (BG) as a function of immersion time in a simulated body fluid (SBF) using atomic force microscopy (AFM). The results obtained for the crystallized BG! were compared to those of hydroxyapatite c- and a-faces. The calcium phosphate layer grows on the crystallized 45S5 B! by multiple two-dimensional nucleatio...
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