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Deliriumin the ICU setting ‐ a subjective and theoretical survey before the imp...
Bragança, J. P.; Rodrigues, G.; Aragão, I.; Teixeira, C.; Quintaneiro, C.Background and Goal of Study: The current definition of delirium comprises acute change or fluctuation in mental status and inattention, accompanied by either altered level of consciousness or disorganized thinking. It is a frequent condition in the ICU and it is associated with longer hospital stay, increase in mortality at 6 months and long-term cognitive impairment, but remains under diagnosed. The Confusion...
The use of non-standard CT conversion ramps for Monte Carlo verification of 6 M...
Zarza-Moreno, M.; Cardoso, I.; Teixeira, Nuno; Jesus, A. P.; Mora, G.Monte Carlo (MC) dose calculation algorithms have been widely used to verify the accuracy of intensity-modulated radiotherapy (IMRT) dose distributions computed by conventional algorithms due to the ability to precisely account for the effects of tissue inhomogeneities and multileaf collimator characteristics. Both algorithms present, however, a particular difference in terms of dose calculation and report. Whe...
Effect of pH and temperature on phytase and biomass production by submerged fer...
Nascimento, J. C. S.; Souza, F. A. S. D.; Porto, Tatiana Souza; Mussatto, Solange I.; Teixeira, J. A.; Porto, Ana L. F.Phytase production and biomass was evaluated in present work by submerged fermentation with Aspergillus niger var. phoenicis URM 4924. Experimental assays were done under different conditions of pH (4.0 to 8.0) and temperature (25 to 35 ºC), and the influence of these variables on the responses was studied through a 22 central composite design and response surface methodology. Phytase and biomass production wer...
Staphylococcus epidermidis biofilms control by N-acetylcysteine and rifampicin
Leite, Bruna; Gomes, F. I.; Teixeira, P.; Souza, Clovis; Pizzolitto, Elisabeth; Oliveira, RosárioMedical device-associated infections caused by Staphylococcus epidermidis usually involve biofilm formation and its eradication is particularly challenging. Although rifampicin has been proving to be one of the most effective antibiotics against S. epidermidis biofilms, its use as a single agent can lead to the acquisition of resistance. Therefore, we assessed the combined effect of rifampicin with N-acetylcyst...
Improved biosurfactant production by a Pseudomonas aeruginosa strain using agro...
Gudiña, Eduardo J.; Rodrigues, Ana I.; Teixeira, J. A.; Rodrigues, L. R.Microbial surfactants are amphipathic molecules produced by a variety of microorganisms that exhibit pronounced surface and emulsifying activities. Biosurfactants can replace synthetic surfactants in environmental and industrial applications, such as bioremediation and microbial enhanced oil recovery. Furthermore, some biosurfactants have been reported as suitable alternatives to synthetic medicines and antimic...
Shift happens: trailing edge contraction associated with recent warming trends ...
Nicastro, K. R.; Zardi, G. I.; Teixeira, Sara; Neiva, J.; Serrão, Ester; Pearson, G. A.Significant effects of recent global climate change have already been observed in a variety of ecosystems, with evidence for shifts in species ranges, but rarely have such consequences been related to the changes in the species genetic pool. The stretch of Atlantic coast between North Africa and North Iberia is ideal for studying the relationship between species distribution and climate change as it includes th...
Production of white wine by Saccharomyces cerevisiae immobilized on grape pomace
Genisheva, Z.; Macedo, S.; Mussatto, Solange I.; Teixeira, J. A.; Oliveira, J. M.White wine was produced with Saccharomyces cerevisiae cells immobilized on grape pomace, by natural adsorption. The support, the main solid waste from the wine industry, consisted of the skins, seeds and stems. Immobilization was tested using different media, namely complex culture medium, raw grape must and diluted grape must. Grape pomace was revealed to be an appropriate support for yeast cell immobilization...
Evaluation of antimicrobial activity of certain combinations of antibiotics aga...
Gomes, F. I.; Teixeira, P.; TeixeiraCeri, H.; Oliveira, RosárioBackground & objectives: Staphylococcus epidermidis is the most common pathogen associated with infections of surgical implants and other prosthetic devices owing to its adhesion and biofilm-forming ability on biomaterials surfaces. The objective of this study was to compare susceptibilities of biofilmgrown cells to single antibiotic and in combination with others to identify those that were effective against S...
The impact of experimental activities on the motivation and acquisition of scie...
Azevedo, Maria Manuel; Fonseca, Fernando; Brito, C.; Andrade, Raquel P.; Palmeirim, I.; Teixeira, Alexandra Sofia PereiraForty students (middle school) participated in the science activity entitled “Scientists for a Day”, developed by the Life and Health Science Research Institute/School of Health Science, University of Minho. The activity consisted in a set of laboratory activities. The general objectives of this activity were to stimulate the pleasure of knowledge, encourage critical views, heighten the interest in science, mot...
Virulence gene expression by staphylococcus epidermidis biofilm cells exposed t...
Gomes, F. I.; Teixeira, P.; Cerca, Nuno; Ceri, H.; Oliveira, RosárioStaphylococcus epidermidis have become important causes of nosocomial infections, as its pathogenesis is correlated with the ability to form biofilms on polymeric surfaces. Production of poly-N-acetylglucosamine (PNAG) is crucial for S. epidermidis biofilm formation and is synthesized by the gene products of the icaADBC gene cluster. Production of PNAG/polysaccharide intercellular adhesin and biofilm formation ...
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