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Vascular and apoptotic changes in the placode of myelomeningocele mice during t...
Reis, J.L.; Correia-Pinto, J.; Monteiro, M.P.; Costa, M.; Hutchins, G.M.JOAQUIM L. REIS, M.D., PH.D.,1,2 JORGE CORREIA-PINTO, M.D., PH.D.,3,4 MARIANA P. MONTEIRO, M.D., PH.D.,1 MADALENA COSTA, B.SC.,1 AND GROVER M. HUTCHINS, M.D.5 1Department of Anatomy, Abel Salazar Institute for the Biomedical Sciences and Unit for Multidisciplinary Biomedical Research, University of Porto; 2Department of Neurosurgery, Santo António General Hospital; 4Department of Pediatric Surgery, São João Hos...
In utero topographic analysis of astrocytes and neuronal cells in the spinal co...
Reis, J.L.; Correia-Pinto, J.; Monteiro, M.P.; Hutchins, G.M.Abstract OBJECT: Myelomeningocele (MMC) is the most severe form of spina bifida causing severe neurological deficits. Injury to the placode has been attributed to in utero aggression. In this study, glial and neuronal cell changes in both number and topography in mice with MMC were investigated during gestation. METHODS: The curly tail/loop-tail mice model of MMC was used, and fetuses were harvested using caesa...
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