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Growth signaling promotes chronological aging in budding yeast by inducing supe...
Weinberger, Martin; Mesquita, Ana Maria Macedo; Carroll, Timothy; Marks, Laura; Hui Yang; Zhaojie Zhang; Ludovico, Paula; Burhans, William CInhibition of growth signaling pathways protects against aging and age-related diseases in parallel with reduced oxidative stress. The relationships between growth signaling, oxidative stress and aging remain unclear. Here we report that in Saccharomyces cerevisiae, alterations in growth signaling pathways impact levels of superoxide anions that promote chronological aging and inhibit growth arrest of stationar...
Electron transfer reactivity and the catalytic activity of hemoglobin incorpora...
Zhou,Hui; Yang,Rongwu; Shang,Libin; Zhu,Zhiqiang; Li,GenxiHemoglobin (Hb) was incorporated in dimethylaminoethyl methacrylate (DMAEMA) to form a film and the film was modified on pyrolytic graphite (PG) electrode. UV-Vis spectra suggested that Hb in the film could keep its secondary structure. Consequently, a pair of stable, well-defined, and quasi-reversible cyclic voltammetric peaks could be observed with the formal potential at -206 mV (vs. saturated calomel electr...
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