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Novel method for combined linkage and genome-wide association analysis finds ev...
Vieland, V.J.; Hallmayer, J.; Huang, Y.; Pagnamenta, A.T.; Pinto, D.; Khan, H.; Monaco, A.P.; Paterson, A.D.; Scherer, S.W.; Sutcliffe, J.S.Member of the Autism Genome Project Consortium: Astrid M. Vicente ; The Autism Genome Project has assembled two large datasets originally designed for linkage analysis and genome-wide association analysis, respectively: 1,069 multiplex families genotyped on the Affymetrix 10 K platform, and 1,129 autism trios genotyped on the Illumina 1 M platform. We set out to exploit this unique pair of resources by analyzi...
Synergistic antitumor effect of TRAIL and adriamycin on the human breast cancer...
Cui,D.D.; Huang,Y.; Mao,S.H.; Chen,S.C.; Qiu,M.; Ji,L.L.; Yi,C.The aim of the present study was to determine the effect of the combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and adriamycin (ADM) on the human breast cancer cell line MCF-7 and to identify potential mechanisms of apoptosis. Cell viability was analyzed by the MTT assay and the synergistic effect was assessed by the Webb coefficient. Apoptosis was quantified using the annexin V-F...
Beneficial effect of recombinant human growth hormone on the intestinal mucosa ...
Yi,C.; Cao,Y.; Wang,S.R.; Xu,Y.Z.; Huang,H.; Cui,Y.X.; Huang,Y.The objective of the present study was to investigate the effects of recombinant human growth hormone (rhGH) on the intestinal mucosa barrier of septic rats and explore its possible mechanism. Female Sprague-Dawley rats were randomized into three groups: control, Escherichia coli-induced sepsis (S) and treatment (T) groups. Groups S and T were subdivided into subgroups 1d and 3d, respectively. Expression of liv...
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