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Nanoparticulate delivery system for insulin: Design, characterization and in vi...
Reis, Catarina Pinto; Ribeiro, António J.; Houng, Simone; Veiga, Francisco; Neufeld, Ronald J.Insulin-loaded alginate-dextran nanospheres were prepared by nanoemulsion dispersion followed by triggered in situ gelation. Nanospheres were characterized for mean size and distribution by laser diffraction spectroscopy and for shape by transmission electron microscopy. Insulin encapsulation efficiency and in vitro release were determined by Bradford protein assay and bioactivity determined in vitro using a ne...
Data: 2007
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Origem: Estudo Geral - Universidade de Coimbra
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