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Uma variante do gene WNK4 está associada à osteoporose mas não à hipertensão na...
Mendes, A.I.; Mascarenhas, M.R.; Matos, S; Sousa, I; Ferreira, J; Barbosa, A.P.; Bicho, M; Jordan, P.Germline mutations in the WNK4 gene originate Gordon syndrome or pseudohypoaldosteronism type II, a familial form of hypertension with hyperkalemia and hypercalciuria. The WNK4 protein encodes a protein kinase involved in the regulation of various renal ion channels. In order to elucidate the contribution of WNK4 genetic variants to hypertension and/or osteoporosis, we analyzed 271 control individuals and a coh...
Response of the growth plate of uremic rats to human growth hormone and cortico...
Barbosa,A.P.F.; Silva,J.D.P.; Fonseca,E.C.; Lopez,P.M.; Fernandes,M.B.C.; Balduino,A.; Duarte,M.E.L.Children with chronic renal failure in general present growth retardation that is aggravated by corticosteroids. We describe here the effects of methylprednisolone (MP) and recombinant human growth hormone (rhGH) on the growth plate (GP) of uremic rats. Uremia was induced by subtotal nephrectomy in 30-day-old rats, followed by 20 IU kg-1 day-1 rhGH (N = 7) or 3 mg kg-1 day-1 MP (N = 7) or 20 IU kg-1 day-1 rhGH ...
Diretrizes para o resgate e conservação da variabilidade genética de espécies a...
LEITE, A. M. C.; SAMPAIO, P. de T. B.; BARBOSA, A. P.; QUISEN, R. C.Sugestoes de estrategias para o resgate e conservacao da variabilidade genetica de Aniba rosaeodora Ducke em Manaus-AM (Brasil), com base em pesquisas anteriores e em observacoes preliminares no campo. Sao abordadas principalmente a distribuicao atual da especie e sua correlacao com as areas de preservacao existentes, habitat, reproducao, dispersao das sementes, variacoes morfologicas, segundo a area de ocorren...
Medical aspects of urinary tract lithiasis.
Barbosa, A P; Unidade de Endocrinologia, Hospital de S. João, Porto.; Medina, J LThe authors review some etiological, clinical and diagnostic aspects of nephrolithiasis, describing briefly the approach that should be taken to study this disease. Some of the practical aspects of its treatment are also discussed. ; The authors review some etiological, clinical and diagnostic aspects of nephrolithiasis, describing briefly the approach that should be taken to study this disease. Some of the pr...
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