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In vivo performance of chitosan/soy-based membranes as wound dressing devices f...
Santos, T. C.; Hoering, B.; Reise, Kathrin; Silva, S. S.; Oliveira, Joaquim M.; Mano, J. F.; Castro, António G.; Reis, R. L.; Griensven, Martijn vanWound management represents a major clinical challenge on what concerns healing enhancement and pain control. The selection of an appropriate dressing plays an important role in both recovery and esthetic ap- pearance of the regenerated tissue. Despite the wide range of available dressings, the progress in the wound care market relies on the increasing interest in using natural-based biomedical products. Herein...
In vivo short and long term host reaction to starch-based scaffolds
Santos, T. C.; Marques, A. P.; Hoering, B.; Martins, A. R.; Tuzlakoglu, K.; Castro, António G.; Griensven, Martijn van; Reis, R. L.The implantation of biomaterials may elicit a host response to this foreign body, and the magnitude of that reaction depends on the host and on the implanted material. The aim of this study was to compare the inflammatory response induced by the implantation of starch-based (SPCL) scaffolds in two implantation rat models: subcutaneous (SC) and intramuscular (IM). Moreover, two methodologies, wet spinning (WS) a...
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