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The Impact of Polymorphic Variations in the 5p15, 6p12, 6p21 and 15q25 Loci on ...

de Mello, RA; Ferreira, M; Soares-Pires, F; Costa, S; Cunha, J; Oliveira, P; Hespanhol, V; Reis, RM

INTRODUCTION: Polymorphic variants in the 5p15, 6p12, 6p21, and 15q25 loci were demonstrated to potentially contribute to lung cancer carcinogenesis. Therefore, this study was performed to assess the role of those variants in non-small cell lung cancer (NSCLC) risk and prognosis in a Portuguese population. MATERIALS AND METHODS: Blood from patients with NSCLC was prospectively collected. To perform an associati...


The Impact of Polymorphic Variations in the 5p15, 6p12, 6p21 and 15q25 Loci on ...

de Mello, RA; Ferreira, M; Soares-Pires, F; Costa, S; Cunha, J; Oliveira, P; Hespanhol, V; Reis, RM

INTRODUCTION: Polymorphic variants in the 5p15, 6p12, 6p21, and 15q25 loci were demonstrated to potentially contribute to lung cancer carcinogenesis. Therefore, this study was performed to assess the role of those variants in non-small cell lung cancer (NSCLC) risk and prognosis in a Portuguese population. MATERIALS AND METHODS: Blood from patients with NSCLC was prospectively collected. To perform an associati...

Data: 2013   |   Origem: Repositório Comum

Sedation with midazolam in flexible bronchoscopy - a prospective study

Rolo, R; Mota, PC; Coelho, F; Alves, D; Fernandes, G; Cunha, J; Hespanhol, V; Magalhães, A

INTRODUCTION: Sedatives have been increasingly used to improve patient comfort during flexible bronchoscopy (FOB). Due to its rapid-onset, anxiolytic and amnestic properties, midazolam is one of the most commonly used sedatives. OBJECTIVES: To evaluate the effect of sedation with midazolam, including patient tolerance, complications and its potential use on a daily routine basis. MATERIAL AND METHODS: A multi-c...


Sedation with midazolam in flexible bronchoscopy - a prospective study

Rolo, R; Mota, PC; Coelho, F; Alves, D; Fernandes, G; Cunha, J; Hespanhol, V; Magalhães, A

INTRODUCTION: Sedatives have been increasingly used to improve patient comfort during flexible bronchoscopy (FOB). Due to its rapid-onset, anxiolytic and amnestic properties, midazolam is one of the most commonly used sedatives. OBJECTIVES: To evaluate the effect of sedation with midazolam, including patient tolerance, complications and its potential use on a daily routine basis. MATERIAL AND METHODS: A multi-c...

Data: 2012   |   Origem: Repositório Comum

Prevalence of asthma in the city of Porto.

Alves, J; Serviço de Pneumologia, Faculdade de Medicina do Porto.; Hespanhol, V; Magalhães, A; Almeida, J; Marques, J A

It is possible that asthma epidemiology will contribute to the definition of asthma precipitant factors. This work is enrolled in an international study co-ordinated by COMAC-EPI. In Oporto, among 137.000 residents in the same town region, a standardised sample of 4.047 male and female individuals aged from 20 to 44 years was defined. A screening questionnaire was sent with a stamped envelope. Four months later...

Data: 1970   |   Origem: Acta Médica Portuguesa

Spirometric alterations caused by hemodialysis. Their relation to changes in th...

Alves, J; Hespanhol, V; Fernandes, J; Marques, E J

The Forced Expiratory Volume in the 1st second (FEV1) and the Forced Vital Capacity (FVC) was determined before and after a hemodialysis (HD), in 61 patients suffering from chronic renal failure (CRF). Before and after the same HD the value of the following parameters were determined: Na; K; Cl; Urea; Creatinine, Ca; P and hematocrit. We found the following values: initial FEV1 91.68%, final FEV1 100.35%, (P le...

Data: 1970   |   Origem: Acta Médica Portuguesa

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia