The global tuberculosis (TB) threat is diffi cult to evaluate in countries with scarce laboratory facilities where little is known about the genetic basis of drug resistance, including the rpoB RRDR (rifampicin resistance determining region) of the Mycobacterium tuberculosis complex (MTC). The present study aimed at performing a preliminary evaluation of rpoB polymorphisms in a DNA set of MTC isolates from Guin...
The diagnosis of tuberculosis is seriously hampered in the absence of standard biosafety laboratory facilities for specimen concentration and Mycobacterium tuberculosis culture. Within a laboratory twinning arrangement,heat-fixed direct smear and sediment from 74 bleach-processed and 20 non-processed specimens from Cumura Hospital, Guinea-Bissau, were sent to Lisbon for molecular evaluation of rifampicin resist...
In the coast of Central Portugal three lagoons were created by the Holocene flooding of diapiric-related depressions but experienced afterwards a significant sediment accumulation. Fast environmental and morphological changes after the Middle Holocene were clearly forced by anthropogenic activities since the Middle Ages and show a strong feedback on the human communities. Erosion in the studied watersheds depen...
Hydrogen bonded liquids like water present a rich thermodynamic behaviour due to the strength and directionality of the bonds. In a recent paper a geometric model based on Bernal's model for liquids was proposed to study the effects of the hydrogen bonds on the phase transitions of water, under pressure and temperature variations. Water molecules were assumed to stay at the vertices of coordination r (r = 4; 5;...
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