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Collagen type IV-related nephropathies in Portugal: pathogenic COL4A5 mutations...
Sá, MJ; Storey, H; Flinter, F; Nagel, M; Sampaio, S; Castro, R; Araújo, JA; Gaspar, MA; Soares, C; Oliveira, A; Henriques, AC; Costa, AG; Abreu, CPPathogenic mutations in genes COL4A3/COL4A4 are responsible for autosomal Alport syndrome (AS) and thin basement membrane nephropathy (TBMN). We used Sanger sequencing to analyze all exons and splice site regions of COL4A3/COL4A4, in 40 unrelated Portuguese probands with clinical suspicion of AS/TBMN. To assess genotype-phenotype correlations, we compared clinically relevant phenotypes/outcomes between homozygo...
Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirol...
Ruiz, JC; Campistol, JM; Grinyó, JM; Mota, A; Prats, D; Gutiérrez, JA; Henriques, ACBACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is partially responsible for the development of chronic allograft nephropathy (CAN). Sirolimus has demonstrated its potential to substitute for CNIs because it lacks significant nephrotoxicity and shows a short-term immunosuppressive capacity comparable with that of cyclosporine. This results in the maintenance of better renal function when cyclosporin...
Renal Osteodystrophy: Histologic Evaluation after Renal Transplantation
Martins, L; Queirós, J; Ferreira, A; Henriques, AC; Sarmento, AM; Pereira, MC; Guimarães, S
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