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Besnoitia besnoiti protein disulfide isomerase (BbPDI): molecular characterizat...

Marcelino, Eduardo; Martins, Tiago M.; Morais, Joana B.; Nolasco, Sofia; Cortes, Helder; Hemphill, Andrew; Leitão, Alexandre; Novo, Carlos

Besnoitia besnoiti is an apicomplexan parasite responsible for bovine besnoitiosis, a disease with a high prevalence in tropical and subtropical regions and re-emerging in Europe. Despite the great economical losses associated with besnoitiosis, this disease has been underestimated and poorly studied, and neither an effective therapy nor an efficacious vaccine is available. Protein disulfide isomerase (PDI) is ...


Application of conventional and real-time fluorescent ITS1 rDNA PCR for detecti...

Cortes, Helder C.E.; Reis, Yara; Gottstein, Bruno; Hemphill, Andrew; Leitão, Alexandre; Müller, Norbert

Besnoitia besnoiti, an apicomplexan protozoan parasite, is the causative agent of bovine besnoitiosis. This infection may dramatically affect body condition, and, in males, lead to irreversible infertility. While identification of clinical cases and their histopathological confirmation is relatively simple to carry out, finding subclinical forms of infection is more difficult, thus a more sensitive test for the...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia