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Ln[DO3A-N-α-(pyrenebutanamido)propionate] complexes: optimized relaxivity and N...

Ferreira, M. F.; Pereira, G.; Martins, A. F.; Martins, C. I. O.; Prata, M. I. M.; Petoud, S.; Toth, E.; Ferreira, P. M. T.; Martins, J. A.

We have proposed recently that the DO3A-N-α-(amino)propionate chelator and its amide conjugates are leads to targeted, high relaxivity, safe contrast agents for magnetic resonance imaging. In this work we illustrate further the expeditious nature and robustness of the synthetic methodologies developed by preparing the DO3A-N-(α-pyrenebutanamido)propionate chelator. Its Gd3+ chelate retains the optimized water e...


NOD2 gene mutations in ulcerative colitis: useless or misunderstood?

Freire, P; Cardoso, R; Figueiredo, P; Donato, MM; Ferreira, M; Mendes, S; Ferreira, AM; Vasconcelos, H; Portela, F; Sofia, C

PURPOSE: NOD2 mutations have been linked to an increased risk of Crohn's disease and to some of its phenotypes. The association between NOD2 mutations and susceptibility to ulcerative colitis (UC) remains somewhat controversial and potential correlations between these mutations and UC phenotype have not been studied. AIM: To assess whether NOD2 mutations are a risk factor for UC in Portugal and if there are any...


Transfusão maciça: actualização: protocolo do hospital

Placido, C; Reis, E; Barra, A; Ferreira, M; Carvalho, R


Eating behaviours in youths : a comparison between female and male athletes and...

Fortes, L. S.; Kakeshita, I. S.; Almeida, S. S.; Gomes, António Rui; Ferreira, M. E. C.

Article first published online: 25 JUL 2013 ; Objective: This study compared the different factors associated with eating behaviours among young female and male athletes and non-athletes. Method: A total of 580 female and male athletes and 362 female and male non-athletes between 10 and 19 years old participated. We used the subscales of the Eating Attitudes Test (EAT-26) to evaluate the factors associated wit...






Eficácia da Cola de Fibrina no Tratamento da Fístula Broncopleural

R., Costa; P., Ferreira; M., Ferreira; R,, Castro; F., Araújo

A prática da pleurodese com substâncias biológicas de características adesivas, tem sido utilizada correntemente em adultos com Fistula Broncopleural (FBP), no entanto, as referências relativas ao seu uso na idade pediátrica são muito escassas.Os autores apresentam um caso de encerramento, com sucesso, de FBP mediante pleurodese com cola de fibrina num recémnascido internado por pneumonia e pneumotórax, submeti...

Data: 2014   |   Origem: Acta Pediátrica Portuguesa

New dextrin nanomagnetogels as contrast agents for magnetic resonance imaging

Gonçalves, C.; Lalatonne, Y.; Melro, L.; Badino, G.; Ferreira, M. F. M.; David, L.; Geraldes, C. F. G. C.; Motte, L.; Martins, J. A.; Gama, F. M.

This study aims at the production and characterization of a “nanomagnetogel” consisting of superparamagnetic iron oxide nanoparticles (g-Fe2O3) stabilized within a hydrophobized-dextrin nanogel. The nanomagnetogel obtained was extensively characterized with respect to physico-chemical (transmission electron microscopy, cryo-scanning electron microscopy, dynamic light scattering, small angle X-ray scattering), m...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia