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The bed nucleus of stria terminalis and the amygdala as targets of antenatal gl...

Oliveira, Mário; Rodrigues, Ana João; Leão, Pedro; Cardona, Diana; Pêgo, José M.; Sousa, Nuno

Rationale: Several human and experimental studies have shown that early life adverse events can shape physical and mental health in adulthood. Stress or elevated levels of glucocorticoids (GCs) during critical periods of development seem to contribute for the appearance of neurospyschiatric conditions such as anxiety and depression, albeit the underlying mechanisms remain to be fully elucidated. Objectives: The...


Mechanisms of initiation and reversal of drug-seeking behavior induced by prena...

Rodrigues, Ana João; Leão, Pedro; Pêgo, José M.; Cardona, Diana; Carvalho, M.; Oliveira, Mário; Costa, Bruno Marques; Carvalho, Ana Franky

We would like to thank the members of the Neuroscience Research Domain at ICVS for all the helpful discussions and suggestions. We are especially thankful to the animal facility caretakers, and to Drs Sara Silva, António Melo and Ana Paula Silva and Dieter Fischer for their help ; Stress and exposure to glucocorticoids (GC) during early life render individuals vulnerable to brain disorders by inducing structur...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia