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Prognostic value of MGMT promoter methylation in glioblastoma patients treated ...

Costa, BM; Caeiro, C; Guimarães, I; Martinho, O; Jaraquemada, T; Augusto, I; Castro, l; Osório, L; Linhares, P; Honavar, M; Resende, M; Nabiço, R

Glioblastoma (GBM) is the most common and aggressive primary brain tumor. The identification of novel molecular prognostic markers of GBM has recently been an area of great interest in neuro-oncology. The methylation status of the MGMT gene promoter is currently a promising molecular prognostic marker, but some controversial data have precluded its clinical use. We analyzed MGMT methylation by methylation-speci...


Prognostic value of MGMT promoter methylation in glioblastoma patients treated ...

Costa, BM; Caeiro, C; Guimarães, I; Martinho, O; Jaraquemada, T; Augusto, I; Castro, l; Osório, L; Linhares, P; Honavar, M; Resende, M; Nabiço, R

Glioblastoma (GBM) is the most common and aggressive primary brain tumor. The identification of novel molecular prognostic markers of GBM has recently been an area of great interest in neuro-oncology. The methylation status of the MGMT gene promoter is currently a promising molecular prognostic marker, but some controversial data have precluded its clinical use. We analyzed MGMT methylation by methylation-speci...

Data: 2010   |   Origem: Repositório Comum

Digestibilidade aparente de rações contendo complexo enzimático para tilápia-do...

Guimarães,I.G.; Falcon,D.R.; Schich,D.; Barros,M.M.; Pezzato,L.E.

Avaliou-se a digestibilidade aparente de cinco rações isoproteicas e isoenergéticas contendo 0; 0,1; 0,2; 0,3 e 0,4g do complexo enzimático Bioenzimaplus (lipase, protease e carboidrase)/kg de ração na alimentação da tilápia-do-nilo. Foram utilizados 100 peixes distribuídos em cinco aquários de alimentação e cinco aquários de coleta de fezes. Os cinco tratamentos foram arranjados em delineamento inteiramente ao...

Data: 2009   |   Origem: OASIS br

Microsurgical reconstruction of the upper extremity. Experience with 24 free fl...

Costa, H; Serviço de Cirurgia Plástica e Reconstrutiva, Hospital de S. João, Faculdade de Medicina do Porto.; Pinto, A; Cunha, C; Conde, A; Guimarães, I

The authors present the experience of 24 clinical cases of microsurgical reconstruction of the upper limb. These reconstructions were accomplished by different microvascular free flaps which were selected according to the type, size and location of the defects, having applied fasciocutaneous, adipofascial, myo, myocutaneous, tendofasciocutaneous, omentum flaps and 2nd toe transfers. The etiology was traumatic i...

Data: 1970   |   Origem: Acta Médica Portuguesa

Microsurgical reconstruction of the head and neck: experience of 63 free flaps.

Costa, H; Serviço Cirurgia Plástica, Hospital S. João, Porto.; Guimarães, I; Cunha, C; Conde, A; Luz, M; Pinto, A; Pinho, C; Freitas, A; Rodrígues, J

The authors present the experience of 63 clinical cases of microsurgical reconstruction of the head and neck. These reconstructions were accomplished by different microvascular free flaps which were selected according to the type, size and location of the defects. Fasciocutaneous, osteofasciocutaneous, adipofascial, myo, myocutaneous, myosseous, jejunum and great omentum flaps were applied. The etiology was tra...

Data: 1970   |   Origem: Acta Médica Portuguesa

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia