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Crosstalk between genetics, gene expression and biochemical markers supports sy...

Iron Related Gene Expression and Biochemical Phenotype Support Iron Homeostasis...

Iron/copper metabolism in Alzheimer’s disease: genetics and biomarkers in a Por...

This work was supported by Fundação Astrazeneca through the “Programa de Apoio à Investigação” . Presented at the “International Conference in Alzheimer’s Disease 2009 ; The distinction between normal aging and Alzheimer's disease (AD) is a relevant step to combat this disease efficiently. Thus, the identification of biomarkers and genetic factors underlying AD pathology is extremely important. Oxidative injur...

Comparison of four verbal memory tests for the diagnosis and predictive value o...

Background: Mild cognitive impairment (MCI) is considered to be an early stage of a neurodegenerative disorder, particularly Alzheimer’s disease, and the clinical diagnosis requires the objective demonstration of cognitive deficits. The aim of the present study was to evaluate the predictive value of MCI for the conversion to dementia when using four different verbal memory tests (Logical Memory, LM; California...

Memory complaints associated with seeking clinical care

Diagnosis of mild cognitive impairment relies on the presence of memory complaints. However, memory complaints are very frequent in healthy people. The objective of this study was to determine the severity and type of memory difficulties presented by elderly patients who seek for clinical help, as compared to the memory difficulties reported by subjects in the community. Assessment of subjective memory complain...

A relação pedagógica entre docente e aluno no ensino do Design

Os elementos pedagogia, aluno e docente possuem um papel fundamental na formação ao nível do ensino superior. Temos assistido ao surgimento de várias mudanças neste paradigma triangular (pedagogia-docente-aluno) que é compartilhado por todos os que direta ou indiretamente estão envolvidos na atual formação dos futuros profissionais. É propósito deste estudo conhecer e compreender melhor o conjunto de medidas a...

Um contributo para o estudo da imagem das cidades enquanto destinos turísticos:...

Tese de dout., Ciências Económicas e Empresariais (Gestão), Faculdade de Economia, Univ. do Algarve, 2012 ; Esta tese concentra-se no estudo da influência dos eventos culturais na problemática da imagem das cidades enquanto destinos turísticos. O principal objectivo da investigação consiste em avaliar a imagem das cidades Capitais Europeias da Cultura 2010 – Istambul, Pécs e Ruhr - enquanto destinos turísticos...

Data mining methods in the prediction of dementia: A real-data comparison of th...

Background: Dementia and cognitive impairment associated with aging are a major medical and social concern. Neuropsychological testing is a key element in the diagnostic procedures of Mild Cognitive Impairment (MCI), but has presently a limited value in the prediction of progression to dementia. We advance the hypothesis that newer statistical classification methods derived from data mining and machine learning...

Measuring Tourists Happiness: the case of the Algarve

Happiness and Quality of Life (QoL) have been receiving attention since many of the social ills have been reduced in the Western World. Happiness is considered one of the contributors to good QoL: if a community has happy citizens, their QoL is viewed as generally good (Veenhoven, 1997). In the same way, tourists’ happiness and QoL have become an important and interesting issue of ...

Mild cognitive impairment: Deficits in cognitive domains other than memory

Patients with mild cognitive impairment (MCI) typically present with memory complaints, but may have mild deficits in other cognitive domains. We compared the neuropsychological profiles of a series of consecutive MCI patients (n = 116) with a control group of healthy elderly subjects (n = 63). The presence of a memory deficit on delayed recall was consistent in the MCI sample, as it was an inclusion criterion ...