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Effect of chaetomellic acid on hematocrit, urine specific gravity and urinary v...

Nogueira, António José M.; Faustino-Rocha, Ana; Teixeira-Guedes, Catarina; Teixeira, Joana; Oliveira, Paula; Colaço, Bruno; Pires, Maria

Chaetomellic acid (CA) is a potent and highly specific inhibitor of ras farnesyl-protein transferase that seems to reduce both functional and histological damage in uninephrectomized rats subjected to renal ischaemia-reperfusion injury. The aim of this work was to evaluate the effect of chronic treatment with CA on hematocrit, urine specific gravity and urinary volume in a model of renal mass reduction. Male Wi...

Data: 2012   |   Origem: Biblioteca Digital do IPB

Effect of chaetomellic acid on hematocrit, urine specific gravity and urinary v...

Nogueira, António José M.; Faustino-Rocha, Ana; Teixeira-Guedes, Catarina; Teixeira, Joana; Oliveira, Paula; Colaço, Bruno; Pires, Maria

Chaetomellic acid (CA) is a potent and highly specific inhibitor of ras farnesyl-protein transferase that seems to reduce both functional and histological damage in uninephrectomized rats subjected to renal ischaemia-reperfusion injury. The aim of this work was to evaluate the effect of chronic treatment with CA on hematocrit, urine specific gravity and urinary volume in a model of renal mass reduction. Male Wi...

Data: 2012   |   Origem: Biblioteca Digital do IPB

Plant aqueous extracts: Antioxidant capacity via haemolysis and bacteriophage

Gião, Maria S.; Leitão, Isabel; Pereira, Ana; Borges, André B.; Guedes, Catarina J.; Fernandes, João C.; Belo, Luís; Santos-Silva, Alice; Hogg, Tim A.

The bacteriophage P22/Salmonella Typhimurium system, as well as human erythrocytes have been used to assay for protection, against forced oxidation caused by hydrogen peroxide, brought about by several aqueous extracts of selected adventitious plants grown in Portugal. This study proved, for the first time, that the aforementioned bacteriophage-based system is a suitable method to assess the antioxidant activit...


Influence of medium buffers on growth of the cyanobacterium Anabaena variabilis...

Guedes, Catarina; Monteiro, Cristina M.; Meireles, Luís A.; Müllner, Katrin; Malcata, F. Xavier


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