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Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirol...
Ruiz, JC; Campistol, JM; Grinyó, JM; Mota, A; Prats, D; Gutiérrez, JA; Henriques, ACBACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is partially responsible for the development of chronic allograft nephropathy (CAN). Sirolimus has demonstrated its potential to substitute for CNIs because it lacks significant nephrotoxicity and shows a short-term immunosuppressive capacity comparable with that of cyclosporine. This results in the maintenance of better renal function when cyclosporin...
Data: 2004
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Origem: Repositório do Centro Hospitalar e Universitário de Coimbra
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