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Preparation of acetazolamide composite microparticles by supercritical antisolv...
Duarte, Ana Rita C.; Roy, C.; Gonzalez, A. V.; Duarte, Catarina M. M.; Subra-Paternault, PascaleThe possibility of preparation of ophthalmic drug delivery systems using compressed anti-solvent technology was evaluated. and RL 100 were used as drug carriers, acetazolamide was the model drug processed. Compressed anti-solvent experiments were carried out as a semi-continuous or a batch operation from a liquid solution of polymer(s) + solute dissolved in acetone. Both techniques allowed the recovery of comp...
Data: 2007
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Origem: RepositóriUM - Universidade do Minho
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