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Long-term changes in corneal structure and tear inflammatory mediators after or...
González-Pérez, Javier; Villa-Collar, César; González-Méijome, José Manuel; Garcia-Porta, Nery; Parafita, Manuel A.PURPOSE: To monitor changes in corneal structure and level of inflammatory mediators in tears of myopic patients following orthokeratology (OK) and laser in situ keratomileusis (LASIK). METHODS: Sixty-two myopic subjects were analyzed in this prospective study. Thirty-two had worn Paragon CRT contact lenses and 30 underwent standard LASIK. Thirty-two control subjects were also recruited. Pachometry and corneal...
Tear film inflammatory mediators during continuous wear of contact lenses and c...
González-Pérez, Javier; Villa-Collar, César; Sobrino Moreiras, Tomás; Lema Gesto, Isabel; González-Méijome, José Manuel; Rodríguez Ares, María T.OBJECTIVES: To study changes in tear film inflammatory mediators following continuous wear of silicone-hydrogel lenses and corneal refractive therapy with reverse geometry contact lenses. DESIGN: A prospective, case-control study. METHODS: Twenty-eight subjects had worn silicone-hydrogel lenses on a 30-night continuous wear basis. Thirty-two subjects had worn corneal refractive therapy lenses on an overnight ...
Topographic paracentral corneal thickness with pentacam and orbscan : effect of...
González-Pérez, Javier; González-Méijome, José Manuel; Rodríguez Ares, María T.; Parafita, Manuel A.Purpose: To evaluate the effect of an acoustic factor (AF) on the comparison of central corneal thickness (CCT) and peripheral corneal thickness (PCT) measurements with Orbscan II and Pentacam. Methods: The CCT and PCT at 1, 2, and 3 radial distances from the corneal apex were measured using Orbscan II and Pentacam in 22 right eyes of 22 healthy adults (7 men, 15 women). Three measures were obtained from each 1...
Corneal epithelial thinning profile induced by long-term wear of hydrogel lenses
González-Pérez, Javier; González-Méijome, José Manuel; Jalbert, Isabelle; Sweeney, Deborah F.; Erickson, PaulPurpose. To characterize the epithelial thickness profile and study the effects of long-term wear of hydrogel lenses on this profile. Methods. A cross-sectional study was designed. Epithelial thickness was evaluated in 15 subjects who had worn one of two types of low oxygen transmissibility (Dk) hydrogel contact lenses for an average of 10 years (range, 7-16) and compared with a group of 18 control subjects who...
Changes in corneal structure with continuous wear of High-Dk Soft contact lense...
González-Méijome, José Manuel; González-Pérez, Javier; Cerviño, Alejandro; Yebra-Pimentel Vilar, Eva; Parafita, Manuel A.Despite numerous studies that have considered the effects of extended wear of high-Dk soft contact lenses on ocular physiology, little attention has been paid to the impact of such lenses on central or peripheral corneal thickness and curvature. The present study aims to report the time course of changes in corneal thickness and curvature that accompanies the 30-night continuous wear of new silicone hydrogel so...
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