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Regulation of alternative splicing of the small GTPase Rac1

Tese de doutoramento, Biologia (Biologia Molecular), 2009, Universidade de Lisboa, Faculdade de Ciências ; Tumours develop through the stepwise acquisition of genetic changes including those affecting signalling pathways that control cell proliferation and survival. The small GTPase Rac1 regulates signalling pathways controlling actin filament dynamics and transcriptional activation. An alternative splicing va...