A doença hemolítica perinatal resulta da passagem placentária de anticorpos do tipo IgG contra antigénios eritrocitários fetais, dando origem a hemólise. A incompatibilidade Rh(D) é a responsável por cerca de 94% casos. As incompatibilidades por antigénios atípicos (anti-c, anti-Kell) apesar de raras, dão origem a quadros graves.Os autores apresentam um caso clínico de isoimunização anti-c num prematuro, I° fil...
The purpose of this work was to synthesize and characterize the thiatetraaza macrocycle 1-thia-4,7,10,13-tetraazacyclopentadecane ([15]aneN4S). Its acid-base behaviour was studied by potentiometry at 25 °C and ionic strength 0.10 M in KNO3. The protonation sequence of this ligand was investigated by 1H-NMR titration that also allowed the determination of protonation constants in D2O. Binding studies of [15]aneN...
Poly(dimethyl siloxane) (PDMS) was surface-polymerized with poly(ethylene glycol)methacrylate (PEGMA) by surface-initiated atom transfer radical polymerization (SI-ATRP) in aqueous media at room temperature. Modification of the PDMS surface followed a three-step procedure: (i) PDMS surface hydroxylation by UV/ozone exposure, immediately followed by (ii) covalent attachment of the initiator, 1-trichlorosilyl-2-(...
Acrylamide (AA) is a well-known industrial chemical classified as a probable human carcinogen. Benign and malignant tumours at different sites, including the mammary gland, have been reported in rodents exposed to AA. This xenobiotic is also formed in many carbohydrate-rich foods prepared at high temperatures. For this reason, AA is an issue of concern in terms of human cancer risk. The epoxide glycidamide (GA)...
We report the development of a new microwave-based synthetic methodology mediated by Woollins’ reagent that allowed an efficient conversion of caffeine into 6-selenocaffeine. A preliminary evaluation on the modulation of antioxidant activity upon selenation of caffeine, using the DPPH assay, indicated a mild antioxidant activity for 6-selenocaffeine, contrasting with caffeine, that exhibited no antioxidant acti...
The fermented and dry meat sausages presents relevant importance in the south of Europe gastronomy, namely in Portugal. According to the increased consumer concern regarding health and food safety, and simultaneously the abusive use of chemical products to control pathogenic flora, it is essential to get knowledge about bacteriocinogenic and technological properties provided by starter strains in meat products....
O golpe de calor é uma emergência médica caracterizada por uma temperatura central ≥ 40ºC, associada a resposta inflamatória sistémica que conduz a disfunção multiorgânica onde predomina a encefalopatia. A incidência é desconhecida, uma vez que é sub-diagnosticada. Os autores apresentam dois casos internados no Serviço de Cuidados Intensivos Pediátricos no período de um ano.
Background: Exercise is positively associated with physical health and psychological well-being. These benefits have been well documented among adults, but fewer studies analyzed the benefits of exercise to younger people (Sallis, Prochaska, & Taylor, 2000). So, it becomes interesting to know the relation between exercise frequency and some health routines, like eating behaviors. This study analyzed the relatio...
A adolescência é uma fase de maior vulnerabilidade para o envolvimento em comportamentos de risco. Paralelamente, o excesso de peso pode ter implicações pessoais e inter-pessoais que podem pôr em causa o bem-estar psicológico dos adolescentes e potenciar o envolvimento em comportamentos de risco. Objectivo: Analisar estudos sobre comportamentos de risco (ferimentos auto-infligidos e consumo de substâncias) num ...
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