Encontrados 2 documentos, a visualizar página 1 de 1
Synthesis of novel Glycoconjugates derived from Alkynyl heterocycles through a ...
Silva, Marília E.; Gonçalves, João Carlos Oliveira; Campos, Ana M. F. Oliveira; Rodrigues, Lígia M.; Esteves, Ana PaulaAccepted author version posted online: 05 Jun 2012 ; The synthesis of a series of novel 1,4-disubstituted 1,2,3-triazole compounds bearing a D-glucose derivative and an heteroaromatic system is described. Alkylation of isatin, 3-methyl-carbazole and one tetrahydro-gamma-carboline with propargyl bromide gave their N-propargyl derivatives in good yields. These compounds further reacted with acetylated D-glucose ...
Synthesis of 5H-pyrido[4,3-b]indole by a modification of Pomeranz-Fritsch isoqu...
Campos, Ana M. F. Oliveira; Gonçalves, João Carlos Oliveira; Rodrigues, Lígia M.; Esteves, Ana Paula5H-Pyrido[4,3-b]indole was obtained from 3-formylindole in 16% overall yield by Jackson and Shannon modification of the Pomeranz-Fristch isoquinoline synthesis. The final cyclisation occurred but the removal of the tosyl group and oxidation of the dihydrocompound was not efficient. Changes in the concentration of the acid catalyst gave 29% as the best yield for the last step. An NMR study of the cyclisation is ...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||