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Alginate microspheres prepared by internal gelation: Development and effect on ...
Silva, Catarina M.; Ribeiro, António J.; Figueiredo, Isabel Vitória; Gonçalves, Alexandra Rocha; Veiga, FranciscoRecombinant human insulin was encapsulated within alginate microspheres by the emulsification/internal gelation technique with the objective of preserving protein stability during encapsulation procedure. The influence of process and formulation parameters was evaluated on the morphology and encapsulation efficiency of insulin. The in vitro release of insulin from microspheres was studied under simulated gastro...
Data: 2006
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Origem: Estudo Geral - Universidade de Coimbra
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