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Cytostatics occupational exposure: genotoxic effects assessment

Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, Miguel

The use of cytostatics drugs in anticancer therapy is increasing. Health care workers can be occupationally exposed to these drugs classified as carcinogenic, mutagenic or teratogenic. Workers may be exposed to this drug, being in the hospital settings the main focus dwelled upon the pharmacy, and nursing personnel. Although the potential therapeutic benefits of hazardous drugs outweigh the risks of side effect...


Biomonitorization in hospital settings with cytostatics occupational exposure

Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, Miguel

Exposure in a hospital setting is normally due to the use of several antineoplastic drugs simultaneously. Nevertheless, the effects of such mixtures at the cell level and on human health in general are unpredictable and unique due to differences in practice of hospital oncology departments, in the number of patients, protection devices available, and the experience and safety procedures of medical staff. Health...


Application of alkaline comet assay in human biomonitoring for genotoxicity: a ...

Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, Miguel

The use of cytostatics drugs in anticancer therapy is increasing. Health care workers can be occupationally exposed to these drugs classified as carcinogenic, mutagenic or teratogenic. Cytostatics drugs are a heterogeneous group of chemicals widely used in the treatment of cancer, nevertheless have been proved to be also mutagens, carcinogens and teratogens. Workers may be exposed to this drug, being in the hos...


The compatibility of earth-based repair mortars with rammed earth substrates

Gomes, M. Idália; Gonçalves, Teresa D.; Faria, Paulina

3rd Historic Mortars Conference, 11-14 September 2013, Glasgow, Scotland ; Earth constructions are susceptible to degradation due to natural or human causes. The degradation of the exterior surface of earth walls is very common, either due to lack of maintenance or to the use of incompatible materials, and often requires the application of a repair mortar. This work analyses experimentally the performance of e...

Data: 2013   |   Origem: Repositório Institucional da UNL

Evaluation of air lime and clayish earth mortars for earthen wall renders

Faria, Paulina; Silva, Vitor; Jamú, Naila; Dias, Inês; Gomes, M. Idália

CIAV2013 – International Conference on Vernacular Architecture, 7º ATP, VerSus, 16-20 october 2013 ; An experimental rammed earth wall was traditionally made with local earth and characterized in terms of superficial hardness, compactness, thermal conductivity and water absorption, in exterior environmental conditions. Two mortars were made with an air lime and a mixture of three washed graduated siliceous san...

Data: 2013   |   Origem: Repositório Institucional da UNL

Pulsed laser deposition of semiconducting nanoparticles : optical emission spec...

Marques, L.; Ramos, Marta M. D.; Gomes, M. J. M.

Memory devices that use seminconductor nanocrystals (NC) for charge storage began to receive considerable attention in recent years due to their excellent performance, high capacity of memory and miniaturization. In order to integrate these materials into devices, formation of NCs and oxide layers with controlled stoichiometry, dimensions and homogeneity are required. Pulsed laser deposition (PLD) techniques ar...


Optical emission spectroscopy study of pulsed laser deposition of semiconductin...

Marques, L.; Ramos, Marta M. D.; Gomes, M. J. M.

Memory devices that use seminconductor nanocrystals (NC) for charge storage began to receive considerable attention in recent years due to their excellent performance, high capacity of memory and miniaturization. In order to integrate these materials into devices, formation of NCs and oxide layers with controlled stoichiometry, dimensions and homogeneity are required. The optimization of nanoparticle synthesis ...


Isolated Bulbar Conjunctival Kaposi's Sarcoma as a Primary Presentation of AIDS...

Maia, S.; Gomes, M.; Oliveira, L.; Torres, P.

Kaposi's sarcoma (KS) is a malignant vascular tumor, caused by the human herpesvirus 8. It is one of the commonest tumors in human immunodeficiency virus (HIV) patients and not uncommonly the first manifestation of acquired immunodeficiency syndrome (AIDS). Case. We present a case of an isolated bulbar conjunctival KS on a 43-year-old HIV positive male, with no other lesions. Excision and cryotherapy were perfo...


Municipal solid waste shear strength parameters defined through laboratorial an...

Cristina Gomes; M. Lurdes Lopes; Paulo J. Venda Oliveira

This paper presents the parameters of municipal solid waste shear strength determined in the laboratory (triaxial tests) and by in situ tests: standard penetration tests (SPT) and cone penetration tests (CPT). The results analyzed here are part of a study carried out on the Santo Tirso landfill (north of Portugal) between 2001 and 2007. The influence of the strain levels, waste composition, and waste age on the...


Bilateral proliferative retinopathy as the initial presentation of chronic myel...

Macedo, M.; Figueiredo, A.; Ferreira, N.; Barbosa, I.; Furtado, M.; Correia, N.; Gomes, M.; Lume, M.; Menéres, M.; Santos, M.; Meireles, M.

The authors report a rare case of a 48-year-old male with chronic myeloid leukemia (CML) who initially presented with a bilateral proliferative retinopathy. The patient complained of recent visual loss and floaters in both eyes (BE). Ophthalmologic evaluation revealed a best corrected visual acuity (BCVA) of 20/50 in the right eye and 20/200 in the left eye (LE). Fundoscopy showed the presence of bilateral peri...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia