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Quantification of Cholesterol Solubilization by Bile Salt Micelles: Implication...

Cholesterol absorption takes place at the intestine. Prior to absorption, and due to its low aqueous solubility, cholesterol must be solubilized in bile salts (BS). Cholesterol is an important molecule for several functions from structural to hormonal. However, excess of cholesterol is implicated in several diseases, namely atherosclerosis and gallstone disease. The understanding of the mechanism beneath choles...