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Calpains are activated by photodynamic therapy but do not contribute to apoptot...
Almeida, Ramiro D.; Gomes, Edgar R.; Carvalho, Arsélio P.; Duarte, Carlos B.Photodynamic therapy (PDT) of cancer is a promising technique based on the formation of singlet oxygen following irradiation of a sensitizer with visible light. In the present work we investigated the role of calpains in PDT, using the human lymphoblastoid CCRF-CEM cells and bisulfonated aluminum phthalocyanine (AlPcS2) as a sensitizer. Photosensitization induced apoptotic cell death and a time-dependent activa...
Data: 2004
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Origem: Estudo Geral - Universidade de Coimbra
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