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Histological alterations found in the ureter during organ preservation and earl...

Figueiredo, AJ; Cunha, MX; Mota, A; Furtado, AL

INTRODUCTION: There are no studies on the phenomena that occur on the ureter during organ preservation and immediately after transplantation. MATERIAL AND METHODS: We studied ureteral fragments obtained during organ harvesting in the cadaver (n = 9), after cold preservation period (n = 18), and immediately after kidney graft reperfusion (n = 126). In addition to the histological analysis, we evaluated the risk ...


Ureteric lesions detected in normally functioning kidney allografts: risk facto...

Figueiredo, AJ; Cunha, MX; Mota, A; Furtado, AL

INTRODUCTION: We characterized the alterations in ureteral biopsies from normally functioning kidney allografts to study risk factors. MATERIALS AND METHODS: We studied 55 ureteral fragments from kidney grafts obtained during cystoscopy for routine double-J stent extraction. We evaluated the type and severity of the lesions, the risk factors for their occurrence, and their relation to the evolution of the trans...


Deposition and passage of transthyretin through the blood-nerve barrier in reci...

Sousa, MM; Ferrão, J; Fernandes, R; Guimarães, A; Geraldes, B; Perdigoto, R; Tomé, L; Mota, O; Negrão, L; Furtado, AL; Saraiva, MJ

Familial amyloid polyneuropathy (FAP) is characterized by deposition of mutated transthyretin (TTR) in the peripheral nervous system. Prior to amyloid fibrils, nonfibrillar TTR aggregates are deposited inducing oxidative stress with increased nitration (3-NT). As the major source of TTR is the liver, liver transplantation (LT) is used to halt FAP. Given the shortage of liver donors, domino LT (DLT) using FAP li...


Reninoma: uma causa rara de hipertensão arterial

Pina, R; Barbosa, B; Morales, J; Correia, J; Teixeira, V; Furtado, AL; Saldanha, MH


Transplantação pancreática

Bastos, M; Campos, MV; Baptista, C; Alves, R; Bastos, C; Mota, A; Carvalheiro, M; Furtado, AL; Ruas, A

A clinic case of simultaneous pancreas/kidney transplantation on a type 1 diabetic patient is described. A six years follow-up was made with both organs functionating and a good quality of live.Then the authors make a review of the available surgical techniques, indications and complications of this form of treatment. A comparison between the Portuguese and the International experience was discussed.


Risk factors for chronic graft dysfunction in 918 renal transplants.

Mota, A; Figueiredo, A; Cunha, FX; Freitas, L; Parada, B; Bastos, C; Furtado, AL





Sources of glucose production in cirrhosis by 2H2O ingestion and 2H NMR analysi...

Perdigoto, R; Furtado, AL; Porto, A; Rodrigues, TB; Geraldes, CF; Jones, JG

Plasma glucose 2H enrichment was quantified by 2H NMR in patients with cirrhosis (n=6) and healthy subjects (n=5) fasted for 16 h and given 2H(2)O to approximately 0.5% body water. The percent contribution of glycogenolysis and gluconeogenesis to glucose production (GP) was estimated from the relative enrichments of hydrogen 5 and hydrogen 2 of plasma glucose. Fasting plasma glucose levels were normal in both g...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia