Encontrados 3 documentos, a visualizar página 1 de 1
Nanoencapsulation of bovine lactoferrin for food and biopharmaceutical applicat...
Balcão, V. M.; Costa, Carla Isabel; Matos, Carla M.; Moutinho, C.; Amorim, Manuela; Pintado, Manuela E.; Gomes, Ana P.; Vila, Marta M.; Teixeira, J. A.Lactoferrin has for long captured the interest of many researchers as a natural compound with a wide variety of uses. Lactoferrin is a monomeric, iron-binding 80 kDa glycoprotein, and appears to be the subfraction of whey with the best documented antiviral, antimicrobial, anticancer and immune modulating/enhancing effects. It belongs to the family of transferrin proteins, and serves to control iron levels in bo...
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 su...
Hafner, Angela V.; Dai, Jing; Gomes, Ana P.; Xiao, Chun-Yang; Palmeira, Carlos M.Cardiac failure is a leading cause of age-related death, though its root cause remains unknown. Mounting evidence implicates a decline in mitochondrial function due to increased opening of the mitochondrial permeability transition pore (mPTP). Here we report that the NAD+-dependent deacetylase SIRT3 deacetylates the regulatory component of the mPTP, cyclophilin D (CypD) on lysine 166, adjacent to the binding si...
Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents...
Varela, Ana T.; Gomes, Ana P.; Simões, Anabela M.; Teodoro, João S.; Duarte, Filipe V.; Rolo, Anabela P.; Palmeira, Carlos M.http://www.sciencedirect.com/science/article/B6WXH-4T7085D-2/2/535e45a8cc0ac06fe24206561a5ee793
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||