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Characterization of post-trancriptional control mechanisms regulating SMN2 gene...

Tese de mestrado. Biologia (Biologia molecular e Genética). Universidade de Lisboa, Faculdade de Ciências, 2010 ; Research has demonstrated that a significant part of gene expression control is taking place at the post-transcriptional level, determining the stability and translation efficiency of mRNA molecules. These regulatory switches are under the control of RNA-binding proteins and microRNAs that associat...