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Differential glutamate-dependent and glutamate-independent adenosine A1 recepto...
Borycz, Janusz; Pereira, M. Fátima; Melani, Alessia; Rodrigues, Ricardo J.; Köfalvi, Attila; Panlilio, Leigh; Pedata, Felicita; Goldberg, Steven R.Adenosine and dopamine are two important modulators of glutamatergic neurotransmission in the striatum. However, conflicting reports exist about the role of adenosine and adenosine receptors in the modulation of striatal dopamine release. It has been previously suggested that adenosine A1 receptors localized in glutamatergic nerve terminals indirectly modulate dopamine release, by their ability to modulate glut...
Blockade of adenosine A2A receptors prevents protein phosphorylation in the str...
Quiroz, César; Gomes, Catarina; Pak, Arlene C.; Ribeiro, Joaquim A.; Goldberg, Steven R.; Hope, Bruce T.; Ferré, Sergi©2006 Society for Neuroscience ; Previous studies have shown that cortical stimulation selectively activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation and immediate early gene expression in striatal GABAergic enkephalinergic neurons. In the present study, we demonstrate that blockade of adenosine A2A receptors with caffeine or a selective A2A receptor antagonist counteracts the striata...
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