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CA-125 AUC as a predictor for epithelial ovarian cancer relapse

Mano, A; Falcão, A; Godinho, I; Santos, J; Leitão, F; Oliveira, CF; Caramona, M

PURPOSE: The aim of the present work was to evaluate the usefulness of CA-125 normalized in time area under the curve (CA-125 AUC) to signalise epithelial ovarian cancer relapse. PATIENTS AND METHODS: Data from a hundred and eleven patients were submitted to two different approaches based on CA-125 AUC increase values to predict patient relapse. In Criterion A total CA-125 AUC normalized in time value (AUC(i)) ...



CA-125 AUC as a new prognostic factor for patients with ovarian cancer

Mano, Antonio; Falcão, Amílcar; Godinho, I.; Santos, J.; Leitão, F.; Oliveira, C.; Caramona, M.

Abstract Objective The aim of the present study was to investigate the usefulness of the CA-125 area under the curve (AUC) as a new kinetic parameter for predicting overall survival in patients with ovarian cancer. In addition, the relationship of CA-125 AUC with other prognostic factors of ovarian cancer was evaluated. Methods Ninety-two patients that underwent primary line chemotherapy within 4 months after ...


CA-125 AUC as a new prognostic factor for patients with ovarian cancer

Mano, A; Falcão, A; Godinho, I; Santos, J; Leitão, F; Oliveira, CF; Caramona, M

OBJECTIVE: The aim of the present study was to investigate the usefulness of the CA-125 area under the curve (AUC) as a new kinetic parameter for predicting overall survival in patients with ovarian cancer. In addition, the relationship of CA-125 AUC with other prognostic factors of ovarian cancer was evaluated. METHODS: Ninety-two patients that underwent primary line chemotherapy within 4 months after submissi...


Valor prognóstico da expressão por imuno-histoquímica do c-erb-2: em doentes so...

Antunes, A; Silva, T; Godinho, I; Amaral, A; Oliveira, CF

INTRODUCTION: The c-erb2 proto-oncogene is a member of the epidermal growth factor receptor family and has been associated with a more aggressive breast tumour biology and resistance to some types of treatments. AIMS: To evaluate the prognostic value of c-erb-2 receptor, from primary breast cancer on tamoxifen therapy. METHODS: We examined 66 paraffin-embedded sections from primary breast cancers. Patients were...


Carcinoma do Endométrio em Mulheres Jovens: caso clínico

Godinho, I; Sousa, R; Silva, T; Regateiro, FJ; Oliveira, CF; Oliveira, HM


Human red blood cells have an enhancing effect on the relative expansion of CD8...

PORTO, B.; FONSECA, A.M.; GODINHO, I.; AROSA, F.A.; PORTO, G.

Cell Prolif. 2001 Dec;34(6):359-67. Human red blood cells have an enhancing effect on the relative expansion of CD8+ T lymphocytes in vitro. Porto B, Fonseca AM, Godinho I, Arosa FA, Porto G. Laboratory of Cytogenetics, Abel Salazar Institute for the Biomedical Sciences (ICBAS), Porto, Portugal. malheiro@icbas.up.pt Abstract The present study was designed to analyse the effect of red blood cells on T-cell pr...


Carcinoma do endométrio em mulheres jovens: a propósito de um caso clínico

Sousa, R; Silva, T; Carvalho, G; Cortesão, P; Franco, S; Godinho, I; Oliveira, CF


Randomised trial with bleomicin, ifosfamid and cisplatin as neoadjuvant chemoth...

Godinho, I; Gervásio, H; Moutinho, JC; Abraúl, E; Raimundo, D; Oliveira, CF


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia