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Rheological and mechanical properties of acellular and cellladen methacrylated ...
Silva-Correia, J.; Gloria, A.; Oliveira, M. B.; Mano, J. F.; Oliveira, Joaquim M.; Ambrosio, L.; Reis, R. L.Tissue engineered hydrogels hold great potential as nucleus pulposus substitutes (NP), as they promote intervertebral disc (IVD) regeneration and re-establish its original function. But, the key to their success in future clinical applications greatly depends on its ability to replicate the native 3D micro-environment and circumvent their limitation in terms of mechanical performance. In the present study, we i...
Hydrogels for nucleus replacement : facing a biomechanical challenge
Reitmaier, S.; Wolfram, U.; Ignatius, A.; Wilke, H. - J.; Gloria, A.; Martín-Martínez, José M.; Correia, Joana Silva; Oliveira, Joaquim M.; Reis, R. L.Hydrogelsareconsideredpromisingfordiscregenerationstrategies.However,itiscurrently unknownwhetherthedestructionofthenaturalinterfacebetweennucleusandsurrounding structurescausedbynucleotomyandaninadequateannulusclosurediminishesthemechan- ical competenceofthedisc.This in vitro studyaimedtoclarifythesemechanismsandto evaluatewhetherhydrogelsareabletorestorethebiomechanicalbehaviourofthedisc. Nucleuspressureinano...
Cytocompatibility of chitosan and collagen-chitosan scaffolds for tissue engine...
Fernandes,Ligia L.; Resende,Cristiane X.; Tavares,Débora S.; Soares,Gloria A.; Castro,Letícia O.; Granjeiro,Jose M.In this work, chitosan and collagen-chitosan porous scaffolds were produced by the freeze drying method and characterized as potential skin substitutes. Their beneficial effects on soft tissues justify the choice of both collagen and chitosan. Samples were characterized using scanning electron microscope, Fourier Transform InfraRed Spectroscopy (FTIR) and thermogravimetry (TG). The in vitro cytocompatibility of...
Clinical-epidemiologic profile of the schistosomal myeloradiculopathy in Pernam...
Araújo,Karina Conceição GM de; Silva,Cristiana da Rosa e; Santos,Alexsandra Glória A dos; Barbosa,Constança Simões; Ferrari,Teresa CAThis was a retrospective descriptive study on a series of cases of schistosomal myeloradiculopathy (SMR) and the aim was to investigate the incidence of this disease and its clinical and epidemiological characteristics in cases diagnosed at three healthcare units in Pernambuco, Brazil between 1994-2006. The data were collected by reviewing the medical records from both the neurological and paediatric outpatient...
Proposição de um reator fotocatalítico para destruição de microrganismos em amb...
Kondo,Márcia Matiko; Orlanda,José Fábio F.; Ferreira,Maria da Glória A. B.; Grassi,Marco TadeuThe TiO2/UV photocatalytic reactor was investigated as an alternative system to inactivate airborne microorganisms. The experiments performed in the absence of the catalyst showed that direct photolysis was not efficient to destruct microorganisms, with only 30% of inactivation. Similar inactivation percentage was obtained using TiO2 in absence of UV radiation. The destruction of microorganisms present in a con...
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