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In vitro and in vivo chitosan membranes testing for peripheral nerve reconstruc...
Simões, M J; Gärtner, A; Shirosaki, Y; Gil da Costa, R M; Cortez, P P; Gartnër, F; Santos, J D; Lopes, M A; Geuna, S; Varejão, A S PTissue regeneration over a large defect with a subsequent satisfactory functional recovery still stands as a major problem in areas such as nerve regeneration or bone healing. The routine technique for the reconstruction of a nerve gap is the use of autologous nerve grafting, but still with severe complications. Over the last decades several attempts have been made to overcome this problem by using biomaterials...
Intracellular Ca2+ concentration in the N1E-115 neuronal cell line and its use ...
Rodrigues, J M; Luís, A L; Lobato, J V; Pinto, M V; Faustino, A; Hussain, N Sooraj; Lopes, M A; Veloso, A P; Freitas, M; Geuna, S; Santos, J DEntubulation repair of peripheral nerve injuries has a lengthy history. Several experimental and clinical studies have explored the effectiveness of many biodegradable and non-degradable tubes with or without addition of molecules and cells. The main objective of the present study was to develop an economical and also an easy way for culturing a neural cell line which is capable of growing, differentiating and ...
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