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Analogies, metaphors, and wondering about the future: Lay sense-making around s...

Marcu, A.; Gaspar, R.; Rutsaert, P.; Seibt, B.; Fletcher, D.; Verbeke, W.; Barnett, J.

Drawing on social representations theory, we explore how the public make sense of the unfamiliar, taking as the example a novel technology: synthetic meat. Data from an online deliberation study and eighteen focus groups in Belgium, Portugal and the UK indicated that the various strategies of sense-making afforded different levels of critical thinking about synthetic meat. Anchoring to genetic modification, met...


Incorporation of 2-styrylchromones in liposomes: preliminaries studies

Carlos, M.; Almeida, D.; Gomes, A.; Fernandes, Eduarda; Lima, José Costa; Silva, Artur; Pinto, Diana; Santos, Clementina M.M.; Cavaleiro, José

Several compounds with a 2-styrylchromone chemical structure have been shown to hold a high antioxidant activity in vitro, at low concentrations, which indicates a potential therapeutic value that needs to be confirmed in vivo [1-2] . The evaluation of the antioxidant potential of 2- styrylcromones, in vivo, is expected to beneficiate from a formulation that delivers the compound to specific target sites. Due t...

Data: 2008   |   Origem: Biblioteca Digital do IPB

Cinco anos de experiência de TMA nos dadores de sangue do Hospital Amadora-Sintra

Soares, F; Gaspar, R; Rebelo, S; Barra, A; Barradas, A

Introdução: O risco de uma transfusão transmitir uma infecção a HIV, HIW e HVC é predominantemente associado a doações em que as infecções se encontram em estádios precoces e escapam aos outros testes de rotina. Assim em 2002 iniciamos o teste de Transcripção Mediada por Amplificação (TMA) aos nossos dadores diminuindo o período de janela das infecções referidas, aumentando a segurança transfusional. Material e...


Antagonist G-mediated targeting and cytotoxicity of liposomal doxorubicin in NC...

Moreira, J. N.; Gaspar, R.

The aim of the present study was to characterize the interactions of antagonist G (H-Arg-D-Trp-N(me)Phe-D-Trp-Leu-Met-NH 2)-targeted sterically stabilized liposomes with the human variant small cell lung cancer (SCLC) H82 cell line and to evaluate the antiproliferative activity of encapsulated doxorubicin against this cell line. Variant SCLC tumors are known to be more resistant to chemotherapy than classic SCL...


Antagonist G-mediated targeting and cytotoxicity of liposomal doxorubicin in NC...

Moreira,J.N.; Gaspar,R.

The aim of the present study was to characterize the interactions of antagonist G (H-Arg-D-Trp-NmePhe-D-Trp-Leu-Met-NH 2)-targeted sterically stabilized liposomes with the human variant small cell lung cancer (SCLC) H82 cell line and to evaluate the antiproliferative activity of encapsulated doxorubicin against this cell line. Variant SCLC tumors are known to be more resistant to chemotherapy than classic SCLC ...

Data: 2004   |   Origem: OASIS br

Association of anti-HBc seropositivity with undetectable or low level anti-HBs ...

Barradas, A; Barra, A; Baptista, F; Soares, F; Gaspar, R; Venâncio, B; Pereira, T

In this data we observed the association between confirmed. Anti-HCV positive and Anti-HBc positive with low level (<100) or undetectable Anti-HBs. b) ./. c) Between May 1995 to December 2001 we collected and analysed 24989 samples from volunteer blood donors. In this samples we performed the following tests Anti?HCV (Ortho), confirmed for PCR (Roche) or RIBA (Innogenetics), Anti-HBc (Dade-Behreing/Abbott, Anti...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia