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From antimicrobial to anticancer peptides. a review
Gaspar, Diana; Veiga, A. Salomé; Castanho, Miguel A. R. B.Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many organisms. Although AMPs have been essentially studied and developed as potential alternatives for fighting infectious diseases, their use as anticancer peptides (ACPs) in cancer therapy either alone or in combination with other conventional drugs has been regarded as a therapeutic strategy to explore. As human cancer remains ...
Novel strategy to produce a drug delivery system for skin regeneration
Gaspar, Diana Patrícia RodriguesSkin lesions are traumatic events that lead to the increase of fluid loss, infections, scarring and locally immunocompromised regions. These injuries can be caused by genetic disorders, acute trauma or even surgical interventions. In these situations, a substantial area of skin can be damaged, often without the possibility of being regenerated. Scientists have put a lot of effort in the development of suitable ...
A biophysical approach to Phospholipase A2 activity and inhibition by non-stero...
Gaspar, Diana Maria DiezDoutoramento em Ciências Farmacêuticas ; PhD in Pharmaceutical Sciences
O significado do consumo de álcool em mulheres abstinentes com diagnóstico de d...
Gaspar, Diana Cristina CoimbraMonografia apresentada à Universidade Fernando Pessoa como parte dos requisitos para a obtenção do grau de Licenciada em Psicologia Clínica. ; O presente trabalho tem como objectivo explorar os significados subjacentes ao consumo de álcool em 10 mulheres que já foram dependentes desta substância. Baseados numa abordagem qualitativa, recorremos, à Grounded Analysis como forma de analisar e compreender o discurs...
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