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Mielite transversa aguda
Sampaio, M. J.; Garrido, A.; Oliveira, M. J.; Vilan, A.; Almeida, R.; Cunha, J.RESUMO Introdução: A retenção urinária aguda é pouco frequente na criança. A presença de alterações no exame neurológico é um dado fundamental para orientar o diagnóstico. Caso clínico: Os autores apresentam o caso de um rapaz de dez anos, sem antecedentes de relevo, com quadro clínico caracterizado por retenção urinária aguda, obstipação e sinais de lesão do primeiro neurónio. A investigação conduziu ao diagnó...
Dual Effect of Nitrate Therapy for Cyclosporine-Induced Hypertension on Vascula...
Reis, F.; Lemos, E. Teixeira de; Almeida, L.; Parada, B.; Garrido, A. P.; Rocha-Pereira, P.; Santos-Silva, A.; Santos-Dias, J.; Dinis, A.The present study sought to evaluate the prevention and reversion effects of isosorbide-5-mononitrate (Is-5-Mn) on the development of hypertension (HT) and on the underlying vascular and platelet morphofunctional disturbances, using an animal model of cyclosporine (CsA)-induced HT. The following rat groups (n = 8) were tested: (1) a control group (orange juice, for 7 weeks); (2) the CsA group (5 mg/kg/d for 7 w...
Systemic and regional hemodynamic effects of enalaprilat infusion in experiment...
Rahal,L.; Garrido,A.G.; Cruz Jr.,R.J.; Rocha e Silva,M.; Poli-de-Figueiredo,L.F.Angiotensin-converting enzyme inhibitors have been shown to improve splanchnic perfusion in distinct shock states. We hypothesized that enalaprilat potentiates the benefits of early fluid resuscitation in severe experimental sepsis, particularly in the splanchnic region. Anesthetized and mechanically ventilated mongrel dogs received an intravenous infusion of live Escherichia coli over a period of 30 min. There...
Short-lasting systemic and regional benefits of early crystalloid infusion afte...
Garrido,A.G.; Poli de Figueiredo,L.F.; Cruz Jr.,R.J.; Silva,E.; Rocha e Silva,M.We investigated the systemic and regional hemodynamic effects of early crystalloid infusion in an experimental model of septic shock induced by intravenous inoculation with live Escherichia coli. Anesthetized dogs received an intravenous infusion of 1.2 x 10(10) cfu/kg live E. coli in 30 min. After 30 min of observation, they were randomized to controls (no fluids; N = 7), or fluid resuscitation with lactated R...
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