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Method for bacteriophage isolation against target Campylobacter strains

Carvalho, Carla A. O. C. M.; Susano, M.; Fernandes, E.; Santos, Sílvio; Gannon, B. W.; Nicolau, Ana; Gibbs, Paul; Teixeira, P.; Azeredo, Joana

Aims: Poultry meat is considered a major source of Campylobacter. This micro-aerobic bacterium is commonly responsible for foodborne illness. This work focuses on the isolation of Campylobacter coli lytic bacteriophages (phages) against target C. coli strains. Methods and Results: A method involving the enrichment of free-range chicken samples in a broth containing the target C. coli strains and salts (CaCl2 an...


The in vivo efficacy of two administration routes of a phage cocktail to reduce...

Carvalho, Carla A. O. C. M.; Gannon, B. W.; Halfhide, D. E.; Santos, Sílvio; Hayes, C. M.; Roe, J. M.; Azeredo, Joana

Background Poultry meat is one of the most important sources of human campylobacteriosis, an acute bacterial enteritis which is a major problem worldwide. Campylobacter coli and Campylobacter jejuni are the most common Campylobacter species associated with this disease. These pathogens live in the intestinal tract of most avian species and under commercial conditions they spread rapidly to infect a high proport...


Two different routes of a phage cocktail administration to Campylobacter spp.-c...

Carvalho, Carla A. O. C. M.; Gannon, B. W.; Halfhide, D. E.; Azeredo, Joana


Safety issues concerning phage therapy for veterinary applications

Azeredo, Joana; Ferreira, E. C.; Gannon, B. W.; Carvalho, Carla A. O. C. M.; Santos, Sílvio; Krylov, V. N.

Phages have been proposed as natural antimicrobial agents to fight bacterial infections in animals. This is supported by several scientific evidences of the efficacy of phage therapy for veterinary applications. However, there are important safety issues that should be taken into consideration when developing a phage product for veterinary applications. For example it is of utmost importance to guarantee that p...


In vitro and in vivo evaluation of campylobacter bacteriophages

Carvalho, Carla A. O. C. M.; Gannon, B. W.; Halfhide, D. E.; Nicolau, Ana; Azeredo, Joana


Bacteriophage therapy in Campylobacter-infected broiler chickens

Carvalho, Carla A. O. C. M.; Gannon, B. W.; Halfhide, D. E.; Nicolau, Ana; Azeredo, Joana


Bacteriophage therapy in salmonella infected broiler chickens

Gannon, B. W.; Halfhide, D. E.; Zammerini, D.; Hayes, C. M.; Krylov, V. N.; Nicolau, Ana; Azeredo, Joana; Roe, J. M.


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia