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Studies on terrein as a new class of proteasome inhibitors
Demasi,M.; Felicio,A. L.; Pacheco,A. O.; Leite,H. G.; Lima,C.; Andrade,L. H.The proteasome is an intracellular multicatalytic protease involved in the cell cycle regulation, signaling response, antigen presentation and apoptosis. Since proteasome inhibitors promote cell death by apoptosis, they have been proposed as new anti-tumoral drugs. Terrein, a secondary metabolite secreted by the fungus Aspergillus terreus, was firstly described in 1935. In the present work we report that terrei...
Avaliação do crescimento de mudas de pinhão manso (Jatropha curcas L.) em recip...
FERREIRA, M. das G. R.; ROCHA, R. B.; SOUZA, V. F. de; RAMALHO, A. R.; LEITE, H. P.O objetivo deste trabalho foi quantificar o efeito dos diferentes volumes de recipiente na formação de mudas de pinhão-manso (Jatropha curcas L.) e no crescimento em campo aos seis meses após o plantio. ; 2009
A recurrent intracardiac mass in a pregnant woman with the antiphospholipid ant...
Matos, V; Serviço de Medicina, Centro Hospitalar de Coimbra.; Pinheiro, B; Maia, P; Leite, H; Coelho, A; Fernandes, AClinical manifestations of the antiphospholipid syndrome result from thromboembolic phenomena that occur in all vascular territories. Cardiac manifestations frequently associated with this syndrome include valvular and myocardial lesions. We present a case report of primary antiphospholipid syndrome in a pregnant young woman with a right atrial mass detected by echocardiography. Its morphological characteristic...
Recurrent intracardiac mass in a pregnant woman with antiphospholipid syndrome.
Matos, V; Medicine Department, Coimbra Hospital Centre.; Pinheiro, B; Maia, P; Leite, H; Coelho, A; Fernandes, AClinical manifestations of the antiphospholipid syndrome result from thromboembolic phenomena that occur in all vascular territories. Cardiac manifestations frequently associated with this syndrome include valvular and myocardial lesions. We present a case report of primary antiphospholipid syndrome in a pregnant young woman with a right atrial mass detected by echocardiography. Its morphological characteristic...
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