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Ciprofloxacin interactions with bacterial protein OmpF: Modelling of FRET from ...
Fernandes, Fábio; Neves, Patrícia; Gameiro, Paula; Loura, Luís M. S.; Prieto, ManuelThe outer membrane protein F (OmpF) is known to play an important role in the uptake of fluoroquinolone antibiotics by bacteria. In this study, the degree of binding of the fluoroquinolone antibiotic ciprofloxacin to OmpF in a lipid membrane environment is quantified using a methodology based on Förster resonance energy transfer (FRET). Analysis of the fluorescence quenching of OmpF is complex as each OmpF mono...
Data: 2007
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Origem: Estudo Geral - Universidade de Coimbra
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